CUSCO
Ayahuasca Retreats

Sacred Valley, Peru · One day ceremony · Twelve guests

Ayahuasca In Cusco

Thirteen hours in daylight, on your feet, at the altitude where the cactus itself grows. This page describes the day from the cup at seven in the morning to the fire at dusk, what the first two hours actually feel like, and what would make us tell you no.

Begin your application › Read the day, hour by hour
12–13

Hours from the cup to the fire

40 min

From where it is cut to where it is boiled

2,800 m

Where it grows, and where you drink it

4 in 5

Applicants who ask are cleared, in writing

In plain terms

A cactus, boiled for twelve hours, drunk at sunrise


San Pedro is a columnar cactus, Echinopsis pachanoi, called huachuma in Quechua. It grows on dry Andean slopes between roughly two and three thousand metres, and the active compound is mescaline. The flesh is sliced, boiled down over about twelve hours into a thick green liquid, and drunk in the morning. Effects last twelve to thirteen hours.

Ceremonial use here is not a recent import. Stone carvings at Chavín de Huántar, north of Lima, show figures holding the cactus and date to roughly three thousand years ago, which makes huachuma the oldest documented plant medicine tradition in the Andes. The Spanish spent three centuries trying to suppress it. The name San Pedro — Saint Peter, who holds the keys — is what survived that.

In Peru this is legal and traditional huachuma practice is recognised as national cultural heritage. It is not legal to carry the cactus, its extracts or mescaline into the United States. That is why the work happens here and stays here.

Plant
Echinopsis pachanoi · huachuma
Active compound
Mescaline, from the whole boiled cactus
Duration
12–13 hours, 7:00 am to dusk
Setting
Outdoors, terraces above the house
Who is with you
One Andean huachumero, two facilitators, twelve guests
Frequency
One day in each seven-night week
Cost
Included in the week · never sold separately
Begin your application ›

Provenance

The only medicine here that grows within sight of the house


On our ayahuasca page we say plainly that the caapi vine and chacruna do not grow at 2,800 metres, so the brew is cooked in the lowlands by the maestros’ own families and carried up. San Pedro is the exact opposite of that sentence. It grows on these slopes, in this light, at this altitude.

Our huachumero cuts it himself from stands within about forty minutes of the house. It is sliced and boiled here, in an open pot, for around twelve hours the day before you drink it. Nothing is bought in, nothing is concentrated, and no isolated mescaline is used at any point. If you ask which cut yours came from, you will get an answer with a place and a date in it.

Andean centres serving Amazonian medicine is normal. It is just rarely said out loud.

A ceremony, hour by hour

What actually happens between sunrise and the fire


Written for the person deciding whether they can physically do this. Times shift with the season and the group, but this is the shape of it.

5:30 am

Waking, and nothing to eat

You have eaten nothing since a light supper the night before, and you drink only water in the morning. Coca tea is available and is the one exception. Dress for cold at dawn and strong sun by ten: layers, a hat with a brim, and shoes you can walk three or four kilometres in.

6:15 am

Walking up to the terrace

Fifteen minutes uphill to a flat agricultural terrace above the house, with the valley opening below it. Blankets, mats and shade are already set out. Phones go into a box before you leave, as they do every ceremony. A physician walks up with the group.

7:00 am

The cup, with the sun still on the ridge

You go to the huachumero one at a time. It is thick, green and bitter in a way that surprises everyone, and you drink it in one go with lime to follow. Dose is set by the huachumero from your body weight and what he has seen of you that week, not by what you ask for. A second, smaller cup is sometimes offered around ten and declining it is a complete sentence.

7:30 am

The two hours nobody writes about

This is the honest part. The first ninety minutes to two hours are physically unpleasant: heaviness, nausea, a strong wish to lie down and be left alone. Roughly half of guests purge once. It is not a crisis, it is not a sign of anything, and it ends. Almost every guest who has read that San Pedro is the gentle one is surprised here.

9:30 am

It turns

The heaviness lifts, usually quite suddenly, and is replaced by clarity and physical energy. Colour and depth sharpen. Most people want to stand up and move, and this is the point at which the day stops being endured and starts being the thing people describe afterwards.

11:00 am

The walk

The group walks slowly to a spring above the old terraces, three or four kilometres over the day with long stops. Nobody is timed and nobody walks alone: two facilitators move with the group and one stays at the terrace with anyone who prefers to remain. Water is carried and offered on a schedule, because thin dry air at altitude dehydrates people faster than they notice.

1:00 pm

The long open middle

Hours four to seven are the peak, and they are wide rather than sharp. You can talk, and many of the conversations guests have here are the ones they were avoiding at home. You can also say nothing for three hours and that is equally normal. This is where San Pedro differs most from a night ceremony: it happens with your eyes open, in your own words, in daylight.

4:00 pm

Coming down while it is still light

The group walks back down. The intensity draws off gradually over two or three hours rather than stopping, which is one of the reasons guests describe this day as easier to carry home than a ceremony that ends at dawn.

6:30 pm

Fire, soup, and the first food in a day

A fire is lit in the courtyard and the kitchen brings simple dieta food. Most guests are extremely hungry and very talkative. Your integration lead is at the fire and this is often the most useful unscheduled conversation of the week.

9:00 pm

A real night’s sleep

Sleep comes easily after San Pedro in a way it does not after ayahuasca, and the following morning is deliberately empty. Nothing is scheduled until the afternoon.

If you need help

Say so, or raise a hand. A facilitator is with you inside a few seconds, at every point of the day including on the walk. You can go back down to the house accompanied at any time and keep the rest of the week.

If you would rather not walk

Then you stay on the terrace with a facilitator, in shade, for as long as you like. Several guests every month choose this and it is not a lesser version of the day.

The day after

Sunburn is the most common complaint, which tells you something about the day. Legs are tired, the mind is unusually quiet, and the next ayahuasca ceremony is at least twenty four hours away.

Choosing

San Pedro, ayahuasca and Bufo, side by side


The short version: ayahuasca is five to six hours in the dark with your eyes closed, San Pedro is twelve to thirteen hours in daylight on your feet, and Bufo is fifteen minutes that removes the question of choice entirely. They are cleared separately and most guests are cleared for some and not others.

How the three medicines at the Sacred Valley house compare in practice.
  San Pedro Ayahuasca Bufo
Duration12–13 hours5–6 hours15–20 minutes
Time of daySunrise to dusk9 pm to first lightMorning, once
WhereOutdoors, terraces and trailDark maloca, on a matOne to one, indoors
Your bodyWalking, eyes openLying still, eyes closedHeld, lying down
Hardest partFirst two hours, then the sunHours two to fourThe first ninety seconds
Can you talk?Yes, and most people doNoNo
In the weekOne day, mid weekFour nightsOnce, if cleared twice
Usually suitsPeople who find the dark harder than the medicineEveryone here; it is the spine of the weekReturning guests, rarely first timers

Not an either/or

San Pedro is not an alternative to ayahuasca and we do not sell a San Pedro-only week. It sits inside the same seven nights, on the long rest day, and guests who are cleared for both consistently say the two do different work. If you want a standalone huachuma week, we are the wrong centre and will tell you so rather than sell you one. See all services.

Straight answers

What you have read online, and what is actually true


San Pedro is ayahuasca’s gentle little brother.

It is gentler in character and considerably harder in demand. Thirteen hours awake at 2,800 metres, in high-altitude sun, walking, having eaten nothing since the previous evening, is the most physically taxing day of the week for most guests. People are surprised by this every single week.

It is basically a nice walk in nature.

Sometimes for an hour it is. It is also two hours of nausea to begin with, and an open middle in which people frequently cry on a trail in front of other people. It is a ceremony that happens to take place outdoors, not a hike with a garnish.

There is no dieta for San Pedro.

Mescaline is not MAO-inhibited, so the tyramine rules that dominate the ayahuasca dieta are less critical for San Pedro on its own. You are not doing it on its own. You are doing it inside a week that contains four ayahuasca ceremonies, so the week’s dieta applies in full.

It is the same as peyote.

Both contain mescaline and there the resemblance ends. Peyote is a slow-growing Mexican cactus under genuine conservation and cultural pressure, and we do not work with it. San Pedro is Andean, fast-growing and not threatened. We also serve the whole boiled cactus rather than isolated mescaline, which is a different experience and a different legal object.

If I am on antidepressants it is safer than ayahuasca.

No. Mescaline is serotonergic and combining it with SSRIs, SNRIs, lithium, tramadol or triptans carries a real serotonin syndrome risk. This is reviewed as carefully as ayahuasca is, and being cleared for one does not clear you for the other.

I can take a cutting home and grow it.

Not into the United States. The cactus, its extracts and mescaline are all controlled there. Do not put anything in a bag, and do not ask a facilitator to help you, because the answer is no and it is not a close call.

Preparation

Six things that decide whether the day goes well


The week’s dieta covers the pharmacology and we send it three weeks out with a grocery list written for US supermarkets. Everything below is specific to spending thirteen hours outdoors at altitude, and it is the part guests underestimate.

Sun, more than you think
UV at 2,800 metres near the equator is severe and the day is a full one. Bring a brimmed hat, long light sleeves and a mineral sunscreen. Sunburn is the single most common complaint the next morning and it is entirely preventable.
Water, measured not loaded
Facilitators carry it and offer it on a schedule. Thin dry air dehydrates you before you feel thirsty, and drinking two litres in one go is its own problem. Follow the schedule rather than your instinct.
An empty stomach
Light supper the night before, nothing solid in the morning, water and coca tea only. Eating beforehand does not reduce the nausea; it extends it.
Shoes and layers
Three or four kilometres on uneven ground. Trail shoes or broken-in trainers, nothing new. It is near freezing at six in the morning and hot by ten, so bring layers you are willing to carry.
Two days of acclimatising
The San Pedro day is deliberately mid week, never in the first two days. How your body handled the altitude on arrival is part of how the physician decides, so tell a facilitator if you slept badly or had headaches rather than pushing through quietly.
Photosensitising medication
Doxycycline for altitude or travel, isotretinoin, some diuretics and certain antibiotics all raise burn risk sharply in this light. List them at intake. People routinely forget the malaria and acne prescriptions.

Screening

Who we say no to, published before you ask


A licensed physician reads every application before a place is offered or a payment taken, and clears each medicine separately. Roughly four applicants in five who ask for San Pedro are cleared for it. Declined applicants are never charged and always receive the reason in writing.

Absolute stops

  • MAOI medication of any kind
  • Diagnosed schizophrenia or bipolar I
  • Uncontrolled hypertension
  • A cardiac event within twelve months
  • Epilepsy or severe liver disease
  • Pregnancy or breastfeeding
  • Being unable to walk unassisted for an hour

Reviewed individually

  • SSRIs and SNRIs, usually a supervised taper
  • Lithium, tramadol, triptans, stimulants
  • Beta blockers and blood pressure medication
  • Poor altitude tolerance in your first two days here
  • Photosensitising medication and severe sun sensitivity
  • A history of fainting or heat exhaustion
  • Knee, hip or back problems that make walking hard

What we ask you to send

  • Every medication with dose and duration
  • Diagnoses, current and past
  • Cardiac and neurological history
  • How you have handled altitude before, if at all
  • Roughly how far you can comfortably walk
  • Supplements, which people forget to list
  • Who at home knows you are going

On the mountain

A physician is with the group all day, not on call from the house. Oxygen, blood pressure monitoring and a defibrillator are at the terrace, the route never leaves radio contact, and a vehicle can reach the trailhead in under ten minutes. It is an hour on sealed road to a Cusco hospital we hold a standing arrangement with.

Not medical advice

These lists are not exhaustive and nothing on this page is medical advice or a claim of therapeutic benefit. Send your file and let the physician decide. If your history is borderline they will say so plainly rather than guess, and a mixed answer across the three medicines is the normal outcome.

Afterwards

The day people describe to their family


Ayahuasca is difficult to explain to someone who was not in the room. San Pedro tends to survive the retelling, because it happened in daylight, in ordinary language, with your eyes open. Guests report it is the day they can actually describe at home — and for a lot of people that makes it the most useful part of the week, not the lightest.

Integration is the same for every medicine here: four calls in the first three months, then quarterly for a year, with the same lead who read your file before you travelled and who was at the fire that evening. Scheduled on your time zone, included in the price, and not upsold at any point.

One practical note. Guests consistently underestimate the first month home. Keep the two days after you land completely empty, hold the dieta one more week, and expect the San Pedro day to keep returning in fragments for a while.

One price, seven nights

San Pedro is included, and never sold to you


There is no separate San Pedro price, and there will not be one. It is part of the $5,800 week for guests who are cleared and who ask for it. We never suggest a second medicine to a guest who did not raise it themselves, because pricing medicines separately gives a centre a financial reason to recommend them.

Four ayahuasca ceremonies

Two Shipibo maestros in each, twelve guests

One San Pedro day

If cleared, and if you ask for it

An optional Kambo session

Cleared separately, on a rest day

Single occupancy room

Nobody is asked to share

Dieta kitchen and plant baths

All meals, all seven nights

Twelve months of integration

Plus transfers from Cusco

Seven nights, all inclusive

$5,800

Payment plans over three or six months. Nothing is charged until a physician confirms your place, and flights and travel insurance are not included.

October 12 to 194 places
November 9 to 167 places
January 18 to 25 · Deepening$6,400
Apply for a week ›

No charge to apply · reviewed within 48 hours

Questions

About San Pedro in Peru


What is San Pedro?
San Pedro is a columnar cactus, Echinopsis pachanoi, called huachuma in Quechua. It grows on dry Andean slopes between roughly 2,000 and 3,000 metres and contains mescaline. Ceremonial use in these mountains is documented archaeologically at Chavín de Huántar going back around three thousand years, which makes it the oldest continuously used plant medicine in the Andes.
How long does a San Pedro ceremony last?
Twelve to thirteen hours. You drink at about seven in the morning, the first two hours are physically uncomfortable, the open middle runs from roughly ten until four, and the day closes around a fire at dusk. It is the longest single ceremony we run and physically the hardest day of the week for most guests.
Is San Pedro legal in Peru?
Yes. The cactus and its ceremonial use are legal in Peru and traditional huachuma practice is recognised as part of the national cultural heritage. It is not legal to carry San Pedro, its extracts or mescaline into the United States, so the work happens here and stays here.
What is the difference between San Pedro and ayahuasca?
Time of day, position and duration. Ayahuasca is five to six hours in a dark room at night, lying on a mat with your eyes closed while maestros sing. San Pedro is twelve to thirteen hours outdoors in daylight, walking, with your eyes open, and you can hold a conversation for most of it. Guests who find the dark harder than the medicine usually find San Pedro the easier door. Neither replaces the other and both are in the same week.
Does San Pedro make you vomit?
Often, in the first two hours, and then it is over. The brew is thick and extremely bitter and roughly half of guests purge once shortly after drinking. Unlike ayahuasca the nausea belongs to the beginning of the day rather than running through it, and most people feel physically well from about the third hour onward.
Can I do San Pedro and ayahuasca in the same week?
Yes, and most cleared guests do. The San Pedro day sits mid week on the long rest day, at least twenty four hours from any ayahuasca ceremony in either direction. They are cleared separately, so being cleared for one does not mean being cleared for the other.
Do I need to be fit?
You need to be able to walk uphill for about an hour at 2,800 metres and to be outdoors in strong sun for a full day. The walking is slow and nobody is timed, but if that is not realistic for you we will say so before you book flights rather than after you arrive. Guests who struggled with the altitude in their first two days here are routinely moved off the San Pedro day.
Can I take my antidepressants?
MAOIs are an absolute stop. SSRIs and SNRIs are reviewed individually because mescaline is serotonergic and the combination carries a real serotonin syndrome risk, and some cases require a supervised taper planned with your own prescriber. Lithium, tramadol, triptans and stimulants are also reviewed individually. We tell you which before you book flights, and we never rush a taper to fit a retreat date.
How much does a San Pedro ceremony cost?
Nothing beyond the retreat. San Pedro is included in the $5,800 seven-night week for guests who are cleared and who ask for it. We do not sell it separately and we never suggest it to a guest who did not raise it, because pricing a second medicine separately gives a centre a financial reason to recommend it.
Is San Pedro the same as mescaline or peyote?
San Pedro and peyote both contain mescaline but they are different plants from different continents of tradition. Peyote is a small Mexican cactus, is slow growing and is under real conservation pressure, and we do not work with it. San Pedro grows fast on Andean slopes and is not threatened. We serve the whole boiled cactus rather than isolated mescaline.
Where does your San Pedro come from?
It is cut by our huachumero from slopes within about forty minutes of the house and boiled on site for twelve hours the day before you drink it. We can tell you which cut yours came from. This is the one medicine we serve that grows where we serve it, which is not true of the ayahuasca, and we say so on the ayahuasca page as well.

No charge to apply · reviewed within 48 hours

Now you know what the day is. Ask whether you are cleared for it.


One application covers all four medicines. A physician reads it, decides San Pedro on its own contraindications, and tells you plainly what is open to you and what is not. Nothing is charged either way, and a mixed answer is the normal one.

Begin your application › See all four services
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